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Female Viagra has been a rumored target of the pharmaceutical industry for almost a decade.  And, now a new category of female sexual desire drugs are under review by the FDA.  Two drugs, Lybrido and Lybridos, could be on the market by 2016 if they pass the test.  The drugs are being developed by Emotional Brain, a Dutch company of 35 employees founded in 2001 by an academic expert in female sexual dysfunction.

Daniel Bergner has written in the in the New York Times Magazine about the difference between these drugs and current ED treatments for men:  “Viagra meddles with the arteries (causing an erection). A female-desire drug would be something else.  It would adjust the primal and executive regions of the brain. It would reach into the psyche.”

From a clinical or physiological perspective, female desire drugs are trying to directly modify the balance of hormones affecting a woman’s feelings of lust in the brain by modifying two chemicals, serotonin and dopamine.

What’s the market for these drugs?  Only time will tell.  Just don’t call them ‘Female Viagra’.

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We shared in February how Elan’s dismantling had turned it into nothing more than a shell company, holding royalties and revenues but divesting all R&D, product development and commercial activities. Such a model has emerged in the pharmaceutical industry, as a financial hedge on future potential commercialization of products.  Royalty Pharma is most aggressive example of these virtual drug companies that are more hedge fund than healthcare.

Royalty made a run at Elan recently to try and acquire its financial assets.  Kelly Martin, Elan’s CEO, seem less than thrilled with the concept, brushing off the overture as folly.  Now Martin has taken a page out of Royalty’s own playbook acquiring a 21% share of future royalties from Theravance in their partnership with Glaxosmithkline.  Elan will make $1B bet that the respiratory

franchise shared by Theravance and GSK will pan out beyond their investment.  The transaction includes four drugs focused on COPD from their partnership to be developed over the next decade.

The move is the first step (?) in Elan’s strategy to rebrand itself following the sales of its share of MS drug Tysabri to its longtime partner Biogen Idec last year.  Cash rich but with no researchers, pipeline or products to sell, Martin promised a ‘constellation of transactions’ to rebuild its commercial portfolio and revenue streams.   The move had Forbes asking whether Elan purposefully overpaid in the deal to spurn the advances from Royalty Pharma and bring shareholders back to Martin’s side.  Or is Theravance just the first star in the constellation that Martin hopes to illuminate?

BioWorld

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Roche considers divestment of glucose meter business

May 21, 2013

Five years ago, diabetes monitoring was the hottest category around for new investment. Statistics and demographics pointed toward an aging global population in the US, Europe and Japan.  In the US, those patients were generally overweight and out of shape.  And, a profitable razor and razorblades distribution model had companies seeing dollar signs. With obesity [...]

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Astellas restructuring R&D, shutters multiple facilities

May 21, 2013

Japan’s Astellas Pharma is taking a cue from its peers in the US and Europe, fundamentally changing its approach to R&D with a move toward efficiency. The company will close facilities at OSI Pharmaceuticals in New York, Perseid Therapeutics in northern California, one facility in Osaka and its corporate research institute in the US. Astellas [...]

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Siemens Healthcare CEO on CNBC

May 20, 2013

Siemens Healthcare CEO & President in North America Greg Sorensen discussing his brain, his teenagers and the medical device tax on CNBC.

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Allergan riding a rollercoaster in the markets

May 14, 2013

Allergan is on a wild ride in the past few days, posting positive financial results yet getting hammered in the stock market for delaying two high potential drug candidates. One of the products focuses on macular degeneration in Allergan’s core ophthalmology business.  The other is an offshoot of their cosmetic eyelash product Lattisse® for application [...]

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Lilly’s rough week: More layoffs and CEO’s health in question

May 13, 2013

Eli Lilly is having a bad week.  First, employees learned that a massive restructuring of the company’s sales force will affect far more employees than was disclosed last month.  Lilly will eliminate 1,624 positions from its U.S. sales force in July. In addition, the company will be losing their CEO temporarily.  Chief Executive John Lechleiter [...]

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Quintiles goes public in mega IPO for life sciences

May 10, 2013

Quintiles CEO Tom Pike celebrated the company’s IPO yesterday, taking public one the largest private companies in the life sciences industry. Quintiles is a huge success story since going private and restructuring its business.  They also have taken advantage of Big Pharma’s shifting strategy toward R&D, with leaner internal teams and thus a greater reliance [...]

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Could one Senator’s retirement help repeal device tax?

May 8, 2013

Senator Max Baucus (D-MT) was the primary contributing author for the Affordable Care Act.  He is also one of the strongest opponents to overturning the 2.3% medical device tax, seeing as he wrote the bill which included it.  However, the Senator has announced his intent to step down next year, which could potentially change the [...]

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Baxter is latest Alzheimer’s failure. Back to square one?

May 7, 2013

Maybe Chris Veihbacher and his team at Sanofi have it right?  Maybe we just don’t know enough about Alzheimer’s and the underlying physiology behind the disease.  This week, yet another promising treatment has fallen apart in Baxter’s Gammagard, an intravenous immunoglobulin (IVIG) which failed in a closely watched phase III trial. It was thought Baxter’s [...]

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